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In humans, active periods of the debilitating disease Multiple Sclerosis (MS) can last for mere minutes or extend to weeks at a time. They're caused by lesions in the brain
that develop, partly heal, and then recur. Research into a cure has
been difficult, because to date scientists have not been able to
replicate these brain recurring symptoms in laboratory mice.
But now, by using a mouse model for diabetes instead, Dr. Dan Frenkel of Tel Aviv University's Department of Neurobiology, working alongside Prof. Yaniv Assaf and Ph.D. student Hilit Levy, may provide a surprising breakthrough for research into a cure for MS. The team has discovered that when mice with Type 1 Diabetes are injected with myelin protein - the insulating material that coats neurons - they experience the periods of relapsing and remitting disability associated with brain lesions in humans. And for the first time, they've been able to monitor this brain lesion process using magnetic resonance imaging.
Dr. Frenkel believes his finding will lead to the development of more effective treatments for MS. This research has been published in Experimental Neurology.
Read Detailed Study
But now, by using a mouse model for diabetes instead, Dr. Dan Frenkel of Tel Aviv University's Department of Neurobiology, working alongside Prof. Yaniv Assaf and Ph.D. student Hilit Levy, may provide a surprising breakthrough for research into a cure for MS. The team has discovered that when mice with Type 1 Diabetes are injected with myelin protein - the insulating material that coats neurons - they experience the periods of relapsing and remitting disability associated with brain lesions in humans. And for the first time, they've been able to monitor this brain lesion process using magnetic resonance imaging.
Dr. Frenkel believes his finding will lead to the development of more effective treatments for MS. This research has been published in Experimental Neurology.
Read Detailed Study
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